The research behind M-Glucan®
M-Glucan® is supported by over 60 publications and a numerous of animal trials including fish and a variety of different mammals as well as safety and mechanism of action studies. All applications have one thing in common –supporting the innate immune system. The technology behind M-Glucan® has been successfully developed for several alternative indications and applications including nutraceuticals (enhanced resistance against bacterial and viral infections), wound care (improved healing of chronic wounds; product Woulgan®), as well as cancer treatment (immunotherapy)1.
When used as a feed ingredient M-Glucan® provides, amongst others, the following benefits:
- Enhance resistance to virus and bacterial infection and reduce mortalities2,3
- Improve resistance to parasites4
- Boosts the efficacy of vaccines
- Improves overall physical health and protects in periods of exceeded stress
- Improved feed conversion and increased growth rate
By incorporating M-Glucan® in the diet of animals/fish, their natural protection against environmental micro-organisms is enhanced. Although these micro-organisms might not generally cause diseases, they can cause large losses if the animals/fish are weak or in some way stressed. The use of M-Glucan® can therefore be a wise investment, especially during disease susceptible periods such as first-feeding, physiological changes, transport, and handling.
- Raa, J. Immune modulation by non-digestible and non-absorbable beta-1,3/1,6-glucan. Microbial Ecology In Health And Disease. 2015; 26
- Yu X, et al., Oral administered particulate yeast-derived glucan promotes hepatitis B virus clearance in a hydrodynamic injection mouse model. PLoS One. 2015;10(4).
- Marakalala MJ, et al., Dectin-1 plays a redundant role in the immunomodulatory activities of β-glucan-rich ligands in vivo. Microbes Infect. 2013;15(6-7):511-5.
- Refstie, S. Effects of dietary yeast cell wall β-glucans and MOS on performance, gut health, and salmon lice resistance in Atlantic salmon (Salmo salar) fed sunflower and soybean meal. Aquaculture. 2009; 305: 109–11